PATENTED FORMULATION

Hawthorn

Hawthorn (Crataegus spp.) Is a thorny shrub from which very interesting substances can be obtained. The active component of this extract are proanthocyanidins (PAC), including vitexin-2-rhamnoside, studied in the scientific literature for its important activities in regulating myocardial activity.

The proanthocyanidins contained in hawthorn have, in fact, the ability to slow down the frequency of heart contractions and, on the contrary, increase the strength of each of these contractions. These two important activities are termed negative chronotropic and positive inotropic.

For this reason, the use of hawthorn in case of arrhythmias and palpitations has been recognized for quite a long time.

Valeriana officinalis, also called mutually valerian, is a common plant widely used in the phytotherapeutic field as from its extraction it is possible to obtain ingredients, which over time have proven themselves as calming remedies in case of anxiety or insomnia.

This activity seems to be due the enhancement of synaptic transmission mediated by GABA, the main inhibitory neurotransmitter in our body. In fact, valerenic acid appears to be able to inhibit the degradation of this neuromediator, thus making it possible to improve the quality of sleep and relaxation.

However, this result is not achievable with any valerian-based preparation. To have this type of activity, the Valeriana officinalis extract must contain at least 0.7% of pure valerenic acid, as its derivatives have no comparable effects.

Valerian

Passionflower

Passiflora, also known as the passionflower, is a herbaceous plant, whose most used species for phytotherapeutic puposese is Passiflora incarnata. The extracts of greatest interest for their rich flavonoid content are obtained from the green parts of this vegetable.

Passiflora are attributed with important activities ranging from the tranquilizing effect to its antispasmodic activity in the intestine, a particularly interesting feature.

This is due to the fact that the flavonoids present in Passionflower according to scientific literature are able to relax intestinal smooth muscles, blocking spastic contraction and instead favoring muscle decontraction.

Passiflora therefore has complementary characteristics to those of other extracts such as those of Hawthorn and Valerian, acting on the visceral somatization parameter typical of subjects with anxious disorders.

The properties of these single plant extracts can be associated and complement each other.

Hawthorn promotes the regular function of the cardiovascular system
Valerian is useful for promoting sleep and relaxation in case of stress
Passionflower has a relaxing action on the intestinal muscles, improving visceral somatization

Each activity of these extracts has been validated by EFSA (European Food Safety Authority) which has conferred the claims relating to their health activities.

Synergy of action

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